HitPredict

Interactor 1: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 31586073, 36526897
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005938 - cell cortex GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2602 Hs			1 1124
+	Hs
		598337 FLNA_HUMAN (1-2602): 0: 2661: 69.59		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1052950 FLNC_HUMAN (6-2602): 0: 1470: 35.38		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		993298 ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725703 ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		963430 SPTB2_HUMAN (6-367): 4.86e-108: 389: 28.65		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		211670 ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (6-282): 2.13e-95: 347: 32.14		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343798 MACF1_HUMAN (16-239): 9.3e-35: 149: 40.69		ANLN_HUMAN (1-1124): 0: 1520: 100.00