HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: NCOA1 (Q15788)
Nuclear receptor coactivator 1 (NCoA-1) (EC 2.3.1.48) (Class E basic helix-loop-helix protein 74) (bHLHe74) (Protein Hin-2) (RIP160) (Renal carcinoma antigen NY-REN-52) (Steroid receptor coactivator 1) (SRC-1)
Gene: NCOA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12569182
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016922 - nuclear receptor binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2440 Hs			1 1441
+	Hs
		261619 NCOR1_HUMAN (1-2440): 0: 780: 100.00		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Hs
		728974 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		AHR_HUMAN (2-833): 8.86e-80: 284: 13.86
+	Hs
		1378167 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Hs
		649178 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		ARNT_HUMAN (1-642): 5.73e-69: 250: 16.45
+	Hs
		1306187 NCOR2_HUMAN (1-2439): 6.74e-134: 473: 34.71		NPAS1_HUMAN (23-506): 1.3e-68: 245: 15.11
+	Hs
		126178 RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40		BMAL1_HUMAN (1-539): 2.88e-105: 350: 16.16
+	Hs
		181569 RCOR1_HUMAN (360-717): 6.64e-75: 260: 19.40		CLOCK_HUMAN (5-833): 1.42e-75: 271: 14.15
+	Hs
		554312 MUC1_HUMAN (1783-2434): 1.7e-42: 173: 12.71		HIF1A_HUMAN (8-798): 3.33e-103: 351: 13.33
+	Hs
		971082 MUC3A_HUMAN (1741-2439): 2.19e-13: 78.9: 10.68		HIF1A_HUMAN (8-798): 3.33e-103: 351: 13.33
+	Hs
		725093 MYH9_HUMAN (302-1007): 2.78e-26: 121: 11.05		NCOA3_HUMAN (1-1343): 5.25e-75: 277: 24.33
+	Dm
		1096484 MYSN_DROME (37-698): 2.18e-23: 111: 12.10		SIMA_DROME (10-822): 7.59e-78: 286: 14.25
+	Hs
		1050581 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		SIM2_HUMAN (25-667): 4.72e-86: 297: 14.75
+	Hs
		649050 MYH10_HUMAN (328-938): 1.08e-27: 125: 10.65		ARNT_HUMAN (1-642): 5.73e-69: 250: 16.45
+	Hs
		649049 MYH9_HUMAN (302-1007): 2.78e-26: 121: 11.05		ARNT_HUMAN (1-642): 5.73e-69: 250: 16.45
+	Dm
		65204 A8DYB0_DROME (519-1020): 3.03e-11: 71.9: 12.34		SIMA_DROME (10-822): 7.59e-78: 286: 14.25
+	Hs
		649145 CIC_HUMAN (505-2041): 4.4e-15: 84.3: 8.05		ARNT_HUMAN (1-642): 5.73e-69: 250: 16.45