HitPredict

Interactor 1: VAMP4 (O75379)
Vesicle-associated membrane protein 4 (VAMP-4)
Gene: VAMP4

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.554

Property	Details
Experiments	24623722, 30021884
Identification Methods	two hybrid, proximity labelling technology, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 141 Hs			1 664
+	Hs
		359669 VAMP1_HUMAN (32-125): 4.3e-28: 101: 30.85		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		359980 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		359837 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		306748 VAMP5_HUMAN (52-118): 5.78e-18: 75.8: 31.34		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00