HitPredict

Interactor 1: VAMP4 (O75379)
Vesicle-associated membrane protein 4 (VAMP-4)
Gene: VAMP4

Interactor 2: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0030669 - clathrin-coated endocytic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 141 Hs			1 215
+	Hs
		261643 VAMP4_HUMAN (1-120): 4.03e-40: 132: 100.00		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		261649 VAMP4_HUMAN (1-120): 4.03e-40: 132: 100.00		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		592170 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		844447 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		850554 VAMP7_HUMAN (15-139): 2.43e-33: 118: 27.20		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		592276 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Sc
		350845 SEC22_YEAST (23-133): 3.08e-25: 97: 17.12		YPT1_YEAST (14-213): 5.55e-88: 259: 39.02
+	Hs
		592192 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		592467 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00
+	Hs
		1079428 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB1B_HUMAN (13-213): 3.05e-87: 257: 41.79
+	Hs
		918878 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18
+	Hs
		844540 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		844474 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		844710 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57
+	Hs
		914092 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		1079324 VAMP3_HUMAN (47-119): 2.22e-26: 96.7: 41.10		RB11B_HUMAN (11-215): 1.27e-82: 246: 40.74
+	Hs
		913996 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		926211 VAMP2_HUMAN (46-122): 9.98e-26: 95.5: 35.07		RB11B_HUMAN (11-215): 1.27e-82: 246: 40.74
+	Hs
		914322 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32
+	Hs
		1079958 VAMP8_HUMAN (41-120): 1.87e-25: 94.3: 27.50		RB11B_HUMAN (11-215): 1.27e-82: 246: 40.74