HitPredict - High confidence protein-protein interactions

Interactor 1: HUS1 (O60921)
Checkpoint protein HUS1 (hHUS1)
Gene: HUS1

Interactor 2: HUS1 (O60921)
Checkpoint protein HUS1 (hHUS1)
Gene: HUS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.55	0.593

Property	Details
Experiments	10777662, 31839598
Identification Methods	two hybrid, affinity chromatography technology, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000077 - DNA damage checkpoint signaling GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm and 13 others more... GO:0005730 - nucleolus GO:0005829 - cytosol GO:0006281 - DNA repair GO:0006289 - nucleotide-excision repair GO:0006974 - DNA damage response GO:0009411 - response to UV GO:0009792 - embryo development ending in birth or egg hatching GO:0030896 - checkpoint clamp complex GO:0031573 - mitotic intra-S DNA damage checkpoint signaling GO:0033314 - mitotic DNA replication checkpoint signaling GO:0035861 - site of double-strand break GO:0044778 - meiotic DNA integrity checkpoint signaling GO:0071479 - cellular response to ionizing radiation
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 11Aug2025