HitPredict - High confidence protein-protein interactions

Interactor 1: PEX14 (O75381)
Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)
Gene: PEX14

Interactor 2: PEX14 (O75381)
Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)
Gene: PEX14

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	10212238, 37071682, 12096124, 21525035
Identification Methods	pull down, cross-linking study, two hybrid, biochemical, ubiquitin reconstruction
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Pex14_N~Pex14_N
Common GO terms	GO:0001650 - fibrillar center GO:0003714 - transcription corepressor activity GO:0005102 - signaling receptor binding GO:0005634 - nucleus GO:0005777 - peroxisome and 21 others more... GO:0005778 - peroxisomal membrane GO:0005829 - cytosol GO:0007031 - peroxisome organization GO:0008017 - microtubule binding GO:0008320 - protein transmembrane transporter activity GO:0016020 - membrane GO:0016558 - protein import into peroxisome matrix GO:0016560 - protein import into peroxisome matrix, docking GO:0016561 - protein import into peroxisome matrix, translocation GO:0030674 - protein-macromolecule adaptor activity GO:0032091 - negative regulation of protein binding GO:0032991 - protein-containing complex GO:0034453 - microtubule anchoring GO:0034614 - cellular response to reactive oxygen species GO:0036250 - peroxisome transport along microtubule GO:0043433 - negative regulation of DNA-binding transcription factor activity GO:0044721 - protein import into peroxisome matrix, substrate release GO:0045892 - negative regulation of DNA-templated transcription GO:0048487 - beta-tubulin binding GO:0065003 - protein-containing complex assembly GO:1990429 - peroxisomal importomer complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	377
Hs

1	377

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Last updated: 15 Jul 2024