Interactor 1: NBN (O60934)
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1) (hNbs1)
Gene: NBN
Interactor 2: CHK2 (O96017)
Serine/threonine-protein kinase Chk2 (EC 2.7.11.1) (CHK2 checkpoint homolog) (Cds1 homolog) (Hucds1) (hCds1) (Checkpoint kinase 2)
Gene: CHEK2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.19 | 0.90 | 0.414 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11438675 |
| Identification Methods | experimental interaction detection |
| Interaction Type | phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FHA~FHA, FHA~Pkinase |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005794 - Golgi apparatus GO:0006302 - double-strand break repair and 2 others more... |
| Homologous interactions | 0 |
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Last updated: 11Aug2025