Interactor 1: TRIM3 (O75382)
Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)
Gene: TRIM3

Interactor 2: RO52 (P19474)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: TRIM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-B_box, zf-B_box~zf-C3HC4
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0061630 - ubiquitin protein ligase activity
GO:0070534 - protein K63-linked ubiquitination
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 744
Hs

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Last updated: 15 Jul 2024