HitPredict

Interactor 1: TRIM3 (O75382)
Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)
Gene: TRIM3

Interactor 2: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0017148 - negative regulation of translation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 744 Hs			1 621
+	Hs
		262160 TRIM3_HUMAN (1-744): 0: 612: 100.00		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Hs
		843877 TRI56_HUMAN (1-742): 7.31e-89: 297: 20.87		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Mm
		1207111 TRIM3_MOUSE (1-744): 0: 610: 98.66		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		729607 TRIM3_MOUSE (1-744): 0: 610: 98.66		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		1142834 TIF1B_MOUSE (16-320): 7.89e-60: 218: 20.89		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Hs
		989105 TRIM2_HUMAN (1-744): 0: 565: 66.67		FMR1_HUMAN (1-506): 0: 599: 51.13
+	Hs
		844217 TRI56_HUMAN (1-742): 7.31e-89: 297: 20.87		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Hs
		734562 TRI23_HUMAN (18-169): 3.18e-13: 75.1: 27.78		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Hs
		989089 TRI56_HUMAN (1-742): 7.31e-89: 297: 20.87		FMR1_HUMAN (1-506): 0: 599: 51.13
+	Mm
		1143829 TIF1B_MOUSE (16-320): 7.89e-60: 218: 20.89		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		729500 TIF1B_MOUSE (16-320): 7.89e-60: 218: 20.89		FMR1_MOUSE (1-506): 0: 599: 51.04