Interactor 1: TRIM3 (O75382)
Tripartite motif-containing protein 3 (EC 2.3.2.27) (Brain-expressed RING finger protein) (RING finger protein 22) (RING finger protein 97)
Gene: TRIM3
Interactor 2: TRIM2 (Q9C040)
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)
Gene: TRIM2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.85 | 1.00 | 0.924 |
The method score is based on:
Property | Details |
---|---|
Experiments | 28514442, 32296183, 33961781, 36481767, unassigned1304 |
Identification Methods | affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Filamin~Filamin, Filamin~NHL, NHL~NHL, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-B_box~zf-C3HC4 |
Common GO terms | GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0008270 - zinc ion binding GO:0017148 - negative regulation of translation GO:0030371 - translation repressor activity and 2 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024