HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	11146101, 20562859, 28253953, 23043107
Identification Methods	two hybrid, affinity chromatography technology, pull down, unspecified method, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0000421 - autophagosome membrane GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005789 - endoplasmic reticulum membrane and 2 others more... GO:0005829 - cytosol GO:0006914 - autophagy
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 117
+	Hs
		262209 ULK1_HUMAN (1-1050): 0: 807: 100.00		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		262317 ULK1_HUMAN (1-1050): 0: 807: 100.00		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		262314 ULK1_HUMAN (1-1050): 0: 807: 100.00		MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11
+	Hs
		262319 ULK1_HUMAN (1-1050): 0: 807: 100.00		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		262316 ULK1_HUMAN (1-1050): 0: 807: 100.00		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		891216 ULK2_HUMAN (9-1044): 0: 688: 50.38		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		306230 ULK2_HUMAN (9-1044): 0: 688: 50.38		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		1223631 ULK2_HUMAN (9-1044): 0: 688: 50.38		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		1223630 ULK2_HUMAN (9-1044): 0: 688: 50.38		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Dm
		1228782 Q8MQJ7_DROME (646-1044): 1.25e-119: 389: 25.92		Q9W2S2_DROME (1-117): 5.35e-58: 176: 57.27
+	Ce
		999349 UNC51_CAEEL (477-1044): 4.39e-80: 281: 21.38		LGG1_CAEEL (1-116): 2.15e-55: 170: 57.76
+	Sc
		746018 ATG1_YEAST (16-273): 4.5e-46: 181: 37.12		ATG8_YEAST (1-116): 1.06e-58: 178: 56.03