HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 30907226, 33545068, 25040165, 25723488, 30335599, 17389358
Identification Methods affinity chromatography technology, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~Pkinase
Common GO terms GO:0000407 - phagophore assembly site
GO:0005737 - cytoplasm
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0006914 - autophagy
and 4 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 440
+ Mm
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024