HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 193
+	Hs
		263212 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		263218 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		263221 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		263210 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		263159 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		263216 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		263209 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		850552 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		850556 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		436215 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		850558 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		850550 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545275 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		850555 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		850548 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		180852 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		180793 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		180850 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		180804 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		180849 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54