HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: STX5 (Q13190)
Syntaxin-5
Gene: STX5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 24705552, 28514442, 33961781, 15029241, 35271311, 22153078
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaptobrevin
Common GO terms GO:0000139 - Golgi membrane
GO:0005484 - SNAP receptor activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 215
Hs

1 355
+ Rn
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+ Dm
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+ At
+ At
+ At
+ At
+ At
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+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024