HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 618
+	Hs
		263159 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		263209 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		263210 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		263244 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		263221 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		263218 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		545275 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		850548 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		850550 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		263215 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		263216 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		263212 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		263365 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		263146 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120240 SC22B_HUMAN (1-215): 6.45e-91: 267: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Sc
		350845 SEC22_YEAST (1-215): 1.97e-66: 205: 35.65		YPT1_YEAST (416-588): 9.61e-32: 123: 18.54
+	Hs
		850552 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		436215 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120358 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564456 VAMP7_HUMAN (31-198): 2.63e-62: 195: 22.62		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26