HitPredict

Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22119785, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 251
+	Hs
		180927 YKT6_HUMAN (30-188): 3.07e-53: 171: 23.13		DERL1_HUMAN (1-251): 9.26e-89: 264: 100.00
+	At
		812694 VA722_ARATH (31-199): 6.71e-74: 224: 23.39		DERL1_ARATH (1-216): 2.33e-65: 205: 30.73
+	At
		1257876 VA723_ARATH (31-199): 7.09e-58: 183: 20.47		DER22_ARATH (3-213): 1.6e-66: 207: 31.08
+	At
		1257872 VA723_ARATH (31-199): 7.09e-58: 183: 20.47		DERL1_ARATH (1-216): 2.33e-65: 205: 30.73