HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: SRS10 (O75494)
Serine/arginine-rich splicing factor 10 (40 kDa SR-repressor protein) (SRrp40) (FUS-interacting serine-arginine-rich protein 1) (Splicing factor SRp38) (Splicing factor, arginine/serine-rich 13A) (TLS-associated protein with Ser-Arg repeats) (TASR) (TLS-associated protein with SR repeats) (TLS-associated serine-arginine protein) (TLS-associated SR protein)
Gene: SRSF10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34316707
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 262
+	Hs
		263877 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PPIE_HUMAN (10-98): 5.42e-30: 115: 31.46
+	Hs
		808521 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (2-99): 1.17e-17: 84: 18.37
+	Hs
		125043 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		266926 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		SRS10_HUMAN (1-262): 2.41e-34: 126: 100.00
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (2-98): 4.25e-20: 91: 24.74
+	Hs
		952117 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35
+	Hs
		125374 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRSF3_HUMAN (1-95): 1.17e-25: 100: 35.79
+	Hs
		125385 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRSF2_HUMAN (4-90): 1.89e-24: 99.3: 45.65
+	Hs
		125430 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP4_HUMAN (2-99): 3.59e-20: 91.3: 18.37
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (2-99): 5.61e-19: 87.9: 17.35