HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: SF3B1 (O75533)
Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155)
Gene: SF3B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 0.60 0.619

The method score is based on:

Property Details
Experiments 35271311, 16055720
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0016607 - nuclear speck
GO:0071004 - U2-type prespliceosome
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 957
Hs

1 1304
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024