HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: FMNL1 (O95466)
Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin)
Gene: FMNL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.605

Property	Details
Experiments	15231748, 16055720
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008360 - regulation of cell shape GO:0016020 - membrane GO:0016477 - cell migration
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 1100
+	Hs
		263795 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		FMNL2_HUMAN (1-1097): 0: 834: 57.31
+	Hs
		154721 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		FMNL1_HUMAN (1-1100): 0: 849: 100.00
+	Hs
		263715 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		FMNL3_HUMAN (1-506): 6.36e-130: 423: 60.90
+	Hs
		263676 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		FMN1_HUMAN (392-1056): 3.02e-93: 328: 21.70
+	Ce
		1176686 Q95PX7_CAEEL (23-819): 1.14e-63: 234: 17.51		Q7JP75_CAEEL (114-1092): 4.92e-126: 421: 19.40
+	Mm
		984960 PR40A_MOUSE (1-957): 5.01e-93: 318: 95.40		FMN1_MOUSE (594-1051): 5.13e-85: 304: 22.41
+	Hs
		263883 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		DAAM1_HUMAN (16-454): 1.14e-57: 219: 19.57
+	Hs
		237540 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		DIAP1_HUMAN (73-391): 1.76e-41: 168: 18.10
+	Hs
		728482 MYH11_HUMAN (528-957): 1.19e-11: 71.1: 10.42		INF2_HUMAN (181-1063): 2.53e-120: 402: 20.27
+	Hs
		724851 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		INF2_HUMAN (181-1063): 2.53e-120: 402: 20.27
+	Mm
		984958 TCRG1_MOUSE (5-820): 2.99e-36: 150: 16.34		FMN1_MOUSE (594-1051): 5.13e-85: 304: 22.41
+	Mm
		984956 WBP4_MOUSE (103-327): 8.48e-29: 121: 18.22		FMN1_MOUSE (594-1051): 5.13e-85: 304: 22.41
+	Hs
		154713 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		DIAP2_HUMAN (33-421): 7.15e-68: 250: 19.24
+	Hs
		154712 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		DIAP1_HUMAN (73-391): 1.76e-41: 168: 18.10
+	Sc
		784665 URN1_YEAST (186-646): 2.61e-58: 209: 12.87		BNI1_YEAST (797-1003): 3.51e-13: 76.6: 26.36
+	Hs
		237541 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		DIAP1_HUMAN (73-391): 1.76e-41: 168: 18.10