HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	25277244
Identification Methods	two hybrid, reverse ras recruitment system
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 205
+	Hs
		388296 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		388717 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		125080 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00
+	Hs
		61510 A5YM51_HUMAN (461-954): 1.75e-10: 67.3: 10.42		HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52
+	Hs
		1356186 MYH4_HUMAN (528-957): 1.55e-09: 64.2: 10.91		HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17