HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 372
+	Hs
		453124 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		453209 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		808665 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44
+	Hs
		609750 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (6-193): 6.86e-35: 137: 17.90
+	Hs
		1290129 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87
+	Hs
		453603 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		125107 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		125640 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87
+	Hs
		453187 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		125156 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		125264 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		808595 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (4-189): 6.12e-39: 147: 24.47
+	Hs
		269205 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		TIA1_HUMAN (99-193): 5.41e-09: 59.4: 17.71
+	Hs
		125447 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		125430 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56