HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30110629
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0007049 - cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 2414
+	Hs
		808548 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Mm
		70879 F8VPR5_MOUSE (15-409): 8.61e-43: 172: 13.29		EP300_MOUSE (1-2414): 0: 1090: 93.01
+	Hs
		269224 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		725147 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		263635 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		551867 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Mm
		101463 F8VPR5_MOUSE (15-409): 8.61e-43: 172: 13.29		TRI33_MOUSE (604-1201): 4.87e-41: 168: 14.81
+	Hs
		154820 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		BRDT_HUMAN (1036-1159): 2.03e-33: 143: 29.84
+	Hs
		154808 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		631372 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20
+	Hs
		725269 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		164449 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26
+	Hs
		808911 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		BRD8_HUMAN (965-1183): 9.91e-16: 86: 19.18
+	Hs
		164478 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26
+	Hs
		808555 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		808609 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		808779 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		KMT2C_HUMAN (416-1078): 1.02e-10: 70.1: 11.13
+	Hs
		808814 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Dm
		113976 M9PB30_DROME (2-350): 4.07e-23: 108: 10.15		M9PB30_DROME (5-444): 3.69e-13: 78.3: 7.05
+	Hs
		554367 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		MUC1_HUMAN (1949-2412): 4.52e-13: 77.5: 9.23