HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 238
+	Hs
		263754 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97
+	Hs
		263569 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		1219665 RHG12_HUMAN (87-632): 2.86e-43: 171: 13.97		PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97
+	Hs
		808654 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00
+	Hs
		432592 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		154788 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		1259877 ITSN2_HUMAN (41-720): 9.42e-36: 149: 9.78		PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97
+	Hs
		516402 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		808925 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		PABP3_HUMAN (6-192): 4.81e-18: 84.4: 14.74
+	Hs
		269201 WBP4_HUMAN (102-385): 6.66e-27: 115: 14.68		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		516643 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		432575 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		952117 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		125268 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		125098 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		125374 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Sc
		376704 PRP40_YEAST (144-667): 4.38e-18: 91.1: 16.90		PABP_YEAST (7-95): 4.44e-17: 81.7: 22.34
+	Hs
		992925 WWP1_HUMAN (22-297): 5.32e-15: 81.7: 13.88		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		125406 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		125122 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11