HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29298432, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 953
+	Hs
		551764 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		154834 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		263878 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		263721 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		725197 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		724906 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		551790 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	Hs
		808869 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		808785 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15
+	Hs
		809031 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		152609 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30
+	Hs
		808609 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73
+	Dm
		113976 M9PB30_DROME (2-350): 4.07e-23: 108: 10.15		M9PB30_DROME (374-952): 2.15e-16: 87.1: 7.48
+	Hs
		1294841 ITCH_HUMAN (4-297): 3.34e-18: 92.1: 13.95		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		125795 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Dm
		54898 SUDX_DROME (80-305): 6.98e-18: 91.4: 13.22		A1ZA72_DROME (31-927): 3.65e-10: 66.6: 13.85
+	Hs
		725139 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63
+	Hs
		724782 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63