HitPredict

Interactor 1: PR40A (O75400)
Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
Gene: PRPF40A

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007049 - cell cycle GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 957 Hs			1 838
+	Hs
		263608 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		263629 PR40A_HUMAN (1-957): 5.9e-97: 328: 100.00		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		551685 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		551705 DESP_HUMAN (419-952): 2.38e-60: 227: 12.98		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		154790 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		154864 TCRG1_HUMAN (6-820): 7.38e-41: 165: 16.47		CHD8_HUMAN (2-836): 0: 635: 26.71
+	Hs
		808948 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CHD8_HUMAN (2-836): 0: 635: 26.71
+	Hs
		808409 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Hs
		808615 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		229338 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SMCA5_HUMAN (75-833): 0: 607: 30.76
+	Hs
		808408 YAP1_HUMAN (34-410): 2.24e-42: 164: 10.05		SMCA2_HUMAN (27-838): 0: 584: 26.37
+	Hs
		725150 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		724799 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		CHD3_HUMAN (50-828): 0: 649: 24.79
+	Hs
		725163 MYH10_HUMAN (432-957): 1.68e-14: 80.8: 9.98		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		125260 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SMCA4_HUMAN (9-838): 0: 633: 24.89
+	Hs
		724833 MYH9_HUMAN (528-957): 1.03e-10: 68.1: 11.11		CHD4_HUMAN (51-828): 0: 630: 25.39
+	Hs
		125173 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SMCA1_HUMAN (104-833): 0: 596: 31.06
+	Hs
		125259 WWP2_HUMAN (4-227): 1.27e-13: 77.3: 12.86		SMCA2_HUMAN (27-838): 0: 584: 26.37
+	Sp
		144920 PRP40_SCHPO (111-742): 1.97e-24: 111: 17.71		FFT3_SCHPO (226-743): 3.04e-77: 271: 33.96