HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 805 Hs			1 1382
+	Rn
		88607 D3ZGN7_RAT (5-805): 2.13e-41: 166: 11.62		INSR_RAT (1-1382): 0: 1527: 94.44
+	Hs
		263992 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Rn
		88517 D3ZAP7_RAT (36-753): 4.08e-38: 156: 10.48		INSR_RAT (1-1382): 0: 1527: 94.44
+	Hs
		263999 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		INSRR_HUMAN (13-1341): 0: 1293: 51.12
+	Hs
		264009 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68
+	Hs
		263994 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63
+	Hs
		665392 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		EPHA3_HUMAN (570-1319): 7.94e-174: 545: 20.56
+	Hs
		665216 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		EPHA2_HUMAN (674-1320): 4.56e-172: 540: 21.91
+	Hs
		263987 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		264118 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53
+	Hs
		169153 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		MUSK_HUMAN (1017-1291): 1.24e-69: 254: 42.22
+	Hs
		264052 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43
+	Hs
		383851 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		383754 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		264006 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		ERBB3_HUMAN (33-369): 1.76e-27: 123: 20.11
+	Hs
		385811 TACC3_HUMAN (35-803): 1.31e-42: 168: 22.72		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		666578 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		LTK_HUMAN (1013-1291): 2e-71: 259: 44.52
+	Hs
		384681 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		674461 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		UFO_HUMAN (789-1294): 1.77e-61: 229: 31.09
+	Hs
		601934 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		ERBB3_HUMAN (33-369): 1.76e-27: 123: 20.11