HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0016020 - membrane GO:0030496 - midbody
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 805 Hs			1 191
+	Hs
		264035 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		264029 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		264000 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		263993 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		264027 TACC1_HUMAN (1-805): 1.32e-103: 339: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		564558 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		1129136 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925335 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		894102 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		951055 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		900556 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545423 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436347 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		892414 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		1129112 CYTSB_HUMAN (69-780): 7.11e-52: 198: 13.92		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		564488 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		925215 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		545334 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		974101 DYST_HUMAN (464-797): 3.16e-33: 141: 9.44		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		297809 K0754_HUMAN (3-803): 4.25e-26: 118: 8.85		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41