HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: CKAP5 (Q14008)
Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG)
Gene: CKAP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.713

Property	Details
Experiments	14603251, 11903063, 26496610, 33961781
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0007052 - mitotic spindle organization GO:0016020 - membrane and 1 others more... GO:0051301 - cell division
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 805 Hs			1 2032
+	Hs
		91405 E7EMZ9_HUMAN (7-804): 5.9e-57: 214: 28.88		CKAP5_HUMAN (1-2032): 0: 1608: 100.00
+	Hs
		311807 TACC2_HUMAN (7-804): 1.65e-49: 192: 26.54		CKAP5_HUMAN (1-2032): 0: 1608: 100.00
+	Hs
		1047856 TACC3_HUMAN (35-803): 1.31e-42: 168: 22.72		CKAP5_HUMAN (1-2032): 0: 1608: 100.00
+	Dm
		90876 Q86BB4_DROME (568-803): 1.32e-64: 217: 25.73		E1JIM4_DROME (1-1992): 0: 1229: 38.36
+	Hs
		672165 TENS2_HUMAN (31-532): 2.18e-36: 150: 11.71		2AAA_HUMAN (656-1045): 2.01e-10: 68: 13.11
+	Hs
		297835 K0754_HUMAN (3-803): 4.25e-26: 118: 8.85		CLAP1_HUMAN (366-1077): 2e-13: 78.6: 8.85
+	Hs
		127176 MUC1_HUMAN (9-367): 1e-15: 83.8: 12.22		IPO5_HUMAN (14-503): 9.94e-12: 72.8: 11.37