Interactor 1: CDC45 (O75419)
Cell division control protein 45 homolog (PORC-PI-1)
Gene: CDC45
Interactor 2: SLD5 (Q9BRT9)
DNA replication complex GINS protein SLD5 (GINS complex subunit 4) [Cleaved into: DNA replication complex GINS protein SLD5, N-terminally processed]
Gene: GINS4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.918 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22374673, 33961781, 23364835, 34195792, 19805216 |
| Identification Methods | fluorescent resonance energy transfer, affinity chromatography technology, bimolecular fluorescence complementation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC45~Sld5 |
| Common GO terms | GO:0000727 - double-strand break repair via break-induced replication GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006268 - DNA unwinding involved in DNA replication GO:0071162 - CMG complex |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
