HitPredict

Interactor 1: GGYF1 (O75420)
GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)
Gene: GIGYF1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23444366
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1035 Hs			1 245
+	Hs
		264290 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		264291 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		264275 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		910330 GGYF1_MOUSE (1-1035): 0: 998: 86.43		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		264276 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		264295 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		264289 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		909707 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		927192 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683470 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		982172 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904743 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Mm
		926889 PLEC_MOUSE (511-899): 1.02e-11: 71.6: 10.47		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		646909 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927068 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		647371 MYH13_HUMAN (491-976): 2.38e-10: 67: 11.61		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927644 MYH13_HUMAN (491-976): 2.38e-10: 67: 11.61		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683340 DCTN1_HUMAN (329-792): 3.09e-09: 63.5: 13.14		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		684048 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982032 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43