HitPredict

Interactor 1: GGYF1 (O75420)
GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)
Gene: GIGYF1

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1035 Hs			1 246
+	Hs
		264290 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		264289 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Mm
		910330 GGYF1_MOUSE (1-1035): 0: 998: 86.43		1433E_MOUSE (1-244): 1.37e-141: 398: 62.71
+	Hs
		264291 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		264275 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		264272 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		264276 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		909707 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904743 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		982172 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		927192 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683470 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		982032 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Mm
		926889 PLEC_MOUSE (511-899): 1.02e-11: 71.6: 10.47		1433Z_MOUSE (3-245): 5.23e-108: 313: 74.49
+	Hs
		927068 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		646909 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		927644 MYH13_HUMAN (491-976): 2.38e-10: 67: 11.61		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683340 DCTN1_HUMAN (329-792): 3.09e-09: 63.5: 13.14		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		647371 MYH13_HUMAN (491-976): 2.38e-10: 67: 11.61		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		684048 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20