HitPredict

Interactor 1: GGYF1 (O75420)
GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)
Gene: GIGYF1

Interactor 2: GRB14 (Q14449)
Growth factor receptor-bound protein 14 (GRB14 adapter protein)
Gene: GRB14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16037382
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1035 Hs			1 540
+	Hs
		264302 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		GRB10_HUMAN (5-540): 0: 551: 54.94
+	Hs
		264308 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		GRB7_HUMAN (63-540): 5.06e-175: 506: 50.21
+	Mm
		1141344 GGYF1_MOUSE (1-1035): 0: 998: 86.43		GRB10_MOUSE (5-88): 2.67e-15: 80.7: 28.57
+	Hs
		1054040 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB14_HUMAN (1-540): 0: 656: 100.00
+	Hs
		1031678 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB10_HUMAN (5-540): 0: 551: 54.94
+	Hs
		1054060 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB7_HUMAN (63-540): 5.06e-175: 506: 50.21
+	Hs
		1068630 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		Q96D37_HUMAN (100-534): 1.77e-99: 319: 16.35
+	Hs
		548710 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		VAV_HUMAN (100-534): 8.93e-99: 319: 16.35
+	Mm
		1141343 GGYF2_MOUSE (546-1035): 7.22e-64: 238: 27.18		GRB10_MOUSE (5-88): 2.67e-15: 80.7: 28.57
+	Hs
		924586 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		GRB2_HUMAN (435-523): 6.87e-28: 112: 31.46
+	Hs
		924566 DCTN1_HUMAN (329-792): 3.09e-09: 63.5: 13.14		GRB2_HUMAN (435-523): 6.87e-28: 112: 31.46