HitPredict

Interactor 1: GGYF1 (O75420)
GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)
Gene: GIGYF1

Interactor 2: GRB7 (Q14451)
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16037382
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1035 Hs			1 532
+	Hs
		264307 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		GRB14_HUMAN (12-532): 0: 614: 47.91
+	Hs
		264302 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		GRB10_HUMAN (1-532): 0: 593: 53.17
+	Mm
		1141344 GGYF1_MOUSE (1-1035): 0: 998: 86.43		GRB10_MOUSE (2-77): 1.15e-12: 72.6: 33.33
+	Hs
		1054060 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB7_HUMAN (1-532): 0: 623: 100.00
+	Hs
		1054040 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB14_HUMAN (12-532): 0: 614: 47.91
+	Hs
		1031678 GGYF2_HUMAN (538-1035): 1.18e-65: 244: 27.03		GRB10_HUMAN (1-532): 0: 593: 53.17
+	Hs
		1068630 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		Q96D37_HUMAN (84-526): 8.36e-87: 286: 15.27
+	Hs
		548710 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		VAV_HUMAN (84-526): 4.42e-86: 285: 15.27
+	Mm
		1141343 GGYF2_MOUSE (546-1035): 7.22e-64: 238: 27.18		GRB10_MOUSE (2-77): 1.15e-12: 72.6: 33.33
+	Hs
		924586 PLEC_HUMAN (511-823): 8.13e-12: 72: 10.90		GRB2_HUMAN (427-513): 2.66e-13: 71: 29.89
+	Hs
		924566 DCTN1_HUMAN (329-792): 3.09e-09: 63.5: 13.14		GRB2_HUMAN (427-513): 2.66e-13: 71: 29.89