HitPredict

Interactor 1: MTX2 (O75431)
Metaxin-2 (Mitochondrial outer membrane import complex protein 2)
Gene: MTX2

Interactor 2: MIC25 (Q9BRQ6)
MICOS complex subunit MIC25 (Coiled-coil-helix cristae morphology protein 1) (Coiled-coil-helix-coiled-coil-helix domain-containing protein 6)
Gene: CHCHD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26496610, 28514442, 32877691, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001401 - SAM complex GO:0005739 - mitochondrion GO:0007007 - inner mitochondrial membrane organization GO:0140275 - MIB complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 263 Hs			1 235
+	Hs
		264647 MTX2_HUMAN (1-263): 3.9e-120: 345: 100.00		MIC19_HUMAN (1-234): 3.39e-73: 224: 35.47
+	Hs
		1136838 FAXC_HUMAN (20-257): 1.09e-78: 244: 23.55		MIC25_HUMAN (1-235): 6.07e-88: 261: 100.00
+	Hs
		1136849 FAXC_HUMAN (20-257): 1.09e-78: 244: 23.55		MIC19_HUMAN (1-234): 3.39e-73: 224: 35.47
+	Hs
		1126190 MTX3_HUMAN (28-255): 7.91e-76: 234: 28.63		MIC19_HUMAN (1-234): 3.39e-73: 224: 35.47