HitPredict

Interactor 1: VP26A (O75436)
Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26)
Gene: VPS26A

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	24344282, 35271311, 34432599
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005829 - cytosol GO:0010008 - endosome membrane GO:0042147 - retrograde transport, endosome to Golgi
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 207
+	Hs
		844961 VP26B_HUMAN (1-325): 3.2e-169: 475: 69.82		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Sc
		701779 PEP8_YEAST (7-298): 6.77e-113: 333: 34.04		YPT7_YEAST (1-207): 3.66e-81: 242: 61.79
+	Hs
		161194 VP26C_HUMAN (41-283): 2.02e-96: 288: 23.27		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00