HitPredict

Interactor 1: USH2A (O75445)
Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein)
Gene: USH2A

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	Hormone_recep~fn3
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 5202 Hs			1 530
+	Hs
		362739 FINC_HUMAN (3020-4714): 1.93e-125: 448: 15.16		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		362738 FINC_HUMAN (3020-4714): 1.93e-125: 448: 15.16		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		490000 PTPRF_HUMAN (1099-1833): 1.27e-26: 123: 12.73		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		433179 LAMB1_HUMAN (892-1076): 2.67e-17: 92.7: 20.76		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1120066 FND3B_HUMAN (1058-1361): 6.44e-15: 84.6: 17.92		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		877435 LAMB2_HUMAN (491-627): 3.69e-11: 72.6: 23.61		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1137772 OBSCN_HUMAN (4172-4360): 1.6e-09: 67.4: 14.06		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1264774 TITIN_HUMAN (2235-2450): 1.46e-09: 67.4: 10.62		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		502858 LAMC1_HUMAN (920-1054): 1.9e-09: 66.6: 30.32		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		172693 LAMA5_HUMAN (482-625): 3.31e-09: 66.2: 12.81		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369741 FND3B_HUMAN (1058-1361): 6.44e-15: 84.6: 17.92		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369564 LAMB3_HUMAN (491-658): 8.23e-13: 77.7: 15.96		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369257 LAMB2_HUMAN (491-627): 3.69e-11: 72.6: 23.61		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370105 TITIN_HUMAN (2235-2450): 1.46e-09: 67.4: 10.62		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		172631 LAMA5_HUMAN (482-625): 3.31e-09: 66.2: 12.81		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377102 TENA_HUMAN (3199-3441): 2.79e-21: 105: 17.34		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		874406 LAMC3_HUMAN (887-1054): 5.38e-14: 81.6: 32.07		NR1H2_HUMAN (49-499): 2.78e-103: 319: 20.86
+	Hs
		377539 TITIN_HUMAN (2235-2450): 1.46e-09: 67.4: 10.62		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		377051 LAMC1_HUMAN (920-1054): 1.9e-09: 66.6: 30.32		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64