HitPredict

Interactor 1: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	33640491, 19762545
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 989 Hs			1 920
+	Hs
		265291 MED24_HUMAN (1-989): 0: 1590: 100.00		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		265302 MED24_HUMAN (1-989): 0: 1590: 100.00		RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84
+	Hs
		265347 MED24_HUMAN (1-989): 0: 1590: 100.00		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Mm
		1142713 MED24_MOUSE (1-989): 0: 1587: 94.24		ERR2_MOUSE (467-904): 1.62e-109: 346: 23.64
+	Hs
		265310 MED24_HUMAN (1-989): 0: 1590: 100.00		HNF4A_HUMAN (536-906): 1e-104: 335: 22.85