HitPredict

Interactor 1: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Interactor 2: THA (P10827)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)
Gene: THRA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	8710870, 10198638, 11117530
Identification Methods	biochemical, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 989 Hs			1 490
+	Hs
		265302 MED24_HUMAN (1-989): 0: 1590: 100.00		RXRA_HUMAN (6-409): 6.39e-113: 343: 24.69
+	Hs
		265291 MED24_HUMAN (1-989): 0: 1590: 100.00		ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04
+	Hs
		265310 MED24_HUMAN (1-989): 0: 1590: 100.00		HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87
+	Mm
		1142713 MED24_MOUSE (1-989): 0: 1587: 94.24		ERR2_MOUSE (1-409): 3.66e-101: 312: 21.41
+	Hs
		265324 MED24_HUMAN (1-989): 0: 1590: 100.00		NR1I3_HUMAN (48-376): 7.96e-40: 149: 32.16
+	Hs
		265309 MED24_HUMAN (1-989): 0: 1590: 100.00		PPARG_HUMAN (52-378): 9.25e-32: 129: 30.70