HitPredict

Interactor 1: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Interactor 2: PPARG (P37231)
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3)
Gene: PPARG

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9653119
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 989 Hs			1 505
+	Hs
		265320 MED24_HUMAN (1-989): 0: 1590: 100.00		PPARA_HUMAN (31-505): 4.22e-120: 362: 54.18
+	Hs
		265302 MED24_HUMAN (1-989): 0: 1590: 100.00		RXRA_HUMAN (21-502): 4.79e-118: 356: 23.22
+	Hs
		265291 MED24_HUMAN (1-989): 0: 1590: 100.00		ESR1_HUMAN (1-501): 9.09e-112: 345: 19.28
+	Hs
		265301 MED24_HUMAN (1-989): 0: 1590: 100.00		VDR_HUMAN (139-503): 4.55e-108: 330: 26.68
+	Mm
		1142713 MED24_MOUSE (1-989): 0: 1587: 94.24		ERR2_MOUSE (25-502): 1.44e-103: 318: 19.75
+	Hs
		265310 MED24_HUMAN (1-989): 0: 1590: 100.00		HNF4A_HUMAN (114-501): 4.62e-100: 311: 21.34
+	Hs
		265347 MED24_HUMAN (1-989): 0: 1590: 100.00		ESR2_HUMAN (23-502): 1.79e-98: 308: 18.70