HitPredict

Interactor 1: MED24 (O75448)
Mediator of RNA polymerase II transcription subunit 24 (Activator-recruited cofactor 100 kDa component) (ARC100) (Cofactor required for Sp1 transcriptional activation subunit 4) (CRSP complex subunit 4) (Mediator complex subunit 24) (Thyroid hormone receptor-associated protein 4) (Thyroid hormone receptor-associated protein complex 100 kDa component) (Trap100) (hTRAP100) (Vitamin D3 receptor-interacting protein complex 100 kDa component) (DRIP100)
Gene: MED24

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	18418385
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 989 Hs			1 837
+	Mm
		1307794 MED24_MOUSE (1-989): 0: 1587: 94.24		KAT2A_MOUSE (1-837): 0: 1161: 97.14
+	Hs
		265304 MED24_HUMAN (1-989): 0: 1590: 100.00		BRD2_HUMAN (691-837): 3.87e-36: 148: 27.63
+	Hs
		265326 MED24_HUMAN (1-989): 0: 1590: 100.00		BRD3_HUMAN (694-833): 1.21e-33: 140: 25.00
+	Hs
		243703 MED24_HUMAN (1-989): 0: 1590: 100.00		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43