HitPredict

Interactor 1: KTNA1 (O75449)
Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin)
Gene: KATNA1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26496610, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0015630 - microtubule cytoskeleton GO:0031122 - cytoplasmic microtubule organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 491 Hs			1 758
+	Hs
		497797 VPS4A_HUMAN (153-489): 7.82e-117: 352: 38.30		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496448 PRS7_HUMAN (30-475): 7.06e-109: 331: 25.22		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		545066 KTNA1_RAT (1-491): 1.16e-151: 443: 93.48		MTAP2_RAT (34-758): 4.12e-36: 149: 28.43
+	Hs
		497280 KATL2_HUMAN (189-490): 4.79e-84: 271: 47.76		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496648 TERA_HUMAN (15-476): 2.39e-79: 265: 26.28		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498014 TERA_MOUSE (15-476): 2.39e-79: 265: 26.28		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		592777 SPAST_MOUSE (4-489): 9.13e-105: 327: 29.70		MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89
+	Mm
		1351631 SPAST_MOUSE (4-489): 9.13e-105: 327: 29.70		PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66