Interactor 1: ERN1 (O75460)
Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]
Gene: ERN1

Interactor 2: ZNRF4 (Q8WWF5)
E3 ubiquitin-protein ligase ZNRF4 (EC 2.3.2.27) (Nixin) (RING finger protein 204) (RING-type E3 ubiquitin transferase ZNRF4) (Zinc/RING finger protein 4)
Gene: ZNRF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 977
Hs

1 429
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024