HitPredict

Interactor 1: E2F6 (O75461)
Transcription factor E2F6 (E2F-6)
Gene: E2F6

Interactor 2: PHC1 (P78364)
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)
Gene: PHC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 281 Hs			1 1004
+	Hs
		265697 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		LMBL3_HUMAN (750-1004): 1.75e-34: 144: 20.91
+	Hs
		1051775 E2F2_HUMAN (3-274): 1.57e-92: 282: 37.42		LMBL3_HUMAN (750-1004): 1.75e-34: 144: 20.91
+	Hs
		135299 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		SMBT1_HUMAN (826-1002): 3.82e-35: 146: 28.57
+	Hs
		135277 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		LMBL3_HUMAN (750-1004): 1.75e-34: 144: 20.91
+	Hs
		963668 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		LMBL3_HUMAN (750-1004): 1.75e-34: 144: 20.91
+	Hs
		135311 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		PCLO_HUMAN (164-938): 1.75e-21: 103: 9.64
+	Hs
		1081363 E2F4_HUMAN (62-261): 4.28e-67: 216: 34.78		LMBL3_HUMAN (750-1004): 1.75e-34: 144: 20.91
+	Hs
		152565 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		KMT2D_HUMAN (9-887): 1.59e-09: 64.6: 8.15
+	Hs
		265683 E2F6_HUMAN (1-281): 2.39e-95: 284: 100.00		PHC3_HUMAN (180-907): 1.62e-09: 64.2: 7.91
+	Hs
		152644 E2F2_HUMAN (3-274): 1.57e-92: 282: 37.42		KMT2D_HUMAN (9-887): 1.59e-09: 64.6: 8.15
+	Mm
		222618 E2F6_MOUSE (1-272): 3.68e-95: 283: 87.13		PHC3_MOUSE (129-831): 6.8e-09: 61.9: 11.95
+	Hs
		135183 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		KMT2D_HUMAN (9-887): 1.59e-09: 64.6: 8.15
+	Hs
		135274 E2F3_HUMAN (7-281): 6.47e-87: 268: 36.10		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86
+	Hs
		963657 E2F1_HUMAN (10-273): 3.43e-85: 263: 35.25		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86
+	Hs
		152652 E2F5_HUMAN (61-273): 4.61e-72: 226: 34.51		KMT2D_HUMAN (9-887): 1.59e-09: 64.6: 8.15
+	Dm
		1099760 E2F1_DROME (7-270): 2.83e-63: 214: 26.51		Q9VLS7_DROME (208-949): 9.32e-11: 68.5: 8.57
+	Hs
		1050525 TFDP1_HUMAN (4-232): 1.64e-61: 201: 17.72		CBP_HUMAN (236-907): 8.37e-09: 61.9: 8.86
+	Dm
		1097284 TFDP_DROME (36-232): 3.08e-40: 146: 17.59		SMBT_DROME (921-1002): 9.57e-13: 74.7: 31.71