Interactor 1: E2F6 (O75461)
Transcription factor E2F6 (E2F-6)
Gene: E2F6

Interactor 2: TFDP2 (Q14188)
Transcription factor Dp-2 (E2F dimerization partner 2)
Gene: TFDP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 25416956, 26186194, 16189514, 9501179, 21516116, 28514442, 27705803, 26871637, 33961781, 32296183, 24981860, 9704927, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, mammalian protein protein interaction trap, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DP~E2F_CC-MB, E2F_TDP~E2F_TDP
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 281
Hs

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Last updated: 15 Jul 2024