Interactor 1: CRLF1 (O75462)
Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)
Gene: CRLF1

Interactor 2: CNTFR (P26992)
Ciliary neurotrophic factor receptor subunit alpha (CNTF receptor subunit alpha) (CNTFR-alpha)
Gene: CNTFR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.681

The method score is based on:

Property Details
Experiments 26858303
Identification Methods surface plasmon resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EpoR_lig-bind~fn3, fn3~fn3
Common GO terms GO:0004896 - cytokine receptor activity
GO:0008284 - positive regulation of cell population proliferation
GO:0009897 - external side of plasma membrane
GO:0019955 - cytokine binding
GO:0043524 - negative regulation of neuron apoptotic process
and 1 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 422
Hs

1 372
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Last updated: 15 Jul 2024