HitPredict

Interactor 1: CRLF1 (O75462)
Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)
Gene: CRLF1

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 296
+	Hs
		1305437 OSMR_HUMAN (13-353): 4.95e-51: 186: 19.20		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		445732 IL6RA_HUMAN (38-346): 1.6e-51: 181: 21.98		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1032042 PTPRS_HUMAN (9-422): 2.32e-28: 120: 14.61		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		685328 L1CAM_HUMAN (46-420): 4.52e-21: 98: 14.03		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1018314 CNTN1_HUMAN (3-412): 1.17e-20: 96.9: 12.88		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		817334 LEPR_HUMAN (221-341): 5.54e-18: 88.4: 27.27		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		770211 IL6RB_HUMAN (17-339): 1.7e-17: 86.9: 14.33		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1032034 PTPRS_HUMAN (9-422): 2.32e-28: 120: 14.61		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1123262 SDK2_HUMAN (9-230): 5.53e-15: 79.5: 13.60		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		789685 LIFR_HUMAN (136-334): 2.58e-10: 64.5: 15.24		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		685320 L1CAM_HUMAN (46-420): 4.52e-21: 98: 14.03		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		817333 LEPR_HUMAN (221-341): 5.54e-18: 88.4: 27.27		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		789684 LIFR_HUMAN (136-334): 2.58e-10: 64.5: 15.24		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81