Interactor 1: NR1I2 (O75469)
Nuclear receptor subfamily 1 group I member 2 (Orphan nuclear receptor PAR1) (Orphan nuclear receptor PXR) (Pregnane X receptor) (Steroid and xenobiotic receptor) (SXR)
Gene: NR1I2

Interactor 2: AP2C (Q92754)
Transcription factor AP-2 gamma (AP2-gamma) (Activating enhancer-binding protein 2 gamma) (Transcription factor ERF-1)
Gene: TFAP2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 21988832
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 434
Hs

1 450
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024