Interactor 1: LGR5 (O75473)
Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38)
Gene: LGR5
Interactor 2: RSPO2 (Q6UXX9)
R-spondin-2 (Roof plate-specific spondin-2) (hRspo2)
Gene: RSPO2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29769720 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Furin-like_2~LRR_8 |
| Common GO terms | GO:0090263 - positive regulation of canonical Wnt signaling pathway |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
