Interactor 1: LGR5 (O75473)
Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38)
Gene: LGR5

Interactor 2: ZNRF3 (Q9ULT6)
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)
Gene: ZNRF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 26123262, 33262293
Identification Methods x-ray crystallography, affinity chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~ZNRF_3_ecto
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 907
Hs

1 936
+ Hs
+ Hs
+ Zm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024