HitPredict

Interactor 1: PSIP1 (O75475)
PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52)
Gene: PSIP1

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 530 Hs			1 664
+	Hs
		360377 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		360295 NSD1_HUMAN (2-529): 5.98e-69: 243: 11.41		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		331683 NSD2_HUMAN (3-444): 2.88e-58: 211: 13.09		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		595392 NSD3_HUMAN (4-445): 6.35e-74: 257: 14.91		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		265944 PSIP1_HUMAN (1-530): 1.2e-79: 260: 100.00		VIME_HUMAN (27-389): 3.94e-31: 129: 28.93
+	Hs
		359779 HDGF_HUMAN (3-225): 5.03e-24: 102: 38.94		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Hs
		360092 HDGR2_HUMAN (1-521): 2.98e-21: 99.5: 20.73		LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00
+	Dr
		71432 NIPLB_DANRE (59-529): 9.62e-16: 82.9: 13.01		B3DKC5_DANRE (9-597): 8e-53: 194: 65.08
+	Hs
		595322 THOC2_HUMAN (106-366): 2.25e-09: 62.4: 14.59		LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37
+	Hs
		422136 NFH_HUMAN (101-366): 3.29e-09: 61.6: 18.08		NFL_HUMAN (28-433): 1.96e-26: 115: 27.07